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Article

RecA-Mediated gene conversion and aminoglycoside resistance in strains heterozygous for rRNA.

Antimicrobial agents and chemotherapy - 1 Mar 1999

Prammananan T, Sander P, Springer B, Böttger E C

Abstract excerpt

Clinical resistance to aminoglycosides in general is due to enzymatic drug modification. Mutational alterations of the small ribosomal subunit rRNA have recently been found to mediate acquired resistance in bacterial pathogens in vivo. In this study we investigated the effect of 16S rRNA heterozy...

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Share to Aminoglycosides
Share to Colony Count, Microbial
Share to Gene Conversion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mycobacterium smegmatis

Share to Rec A Recombinases

Share to Ribonucleases

Share to RNA, Ribosomal

Share to Transformation, Bacterial

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Identifiers

PMID: 10049249
DOI: 10.1128/AAC.43.3.447
PMCID: PMC89142

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-10049249-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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