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Article

Introducing mutations into a chromosomal rRNA gene using a genetically modified eubacterial host with a single rRNA operon.

Molecular microbiology - 1 Dec 1996

Sander P, Prammananan T, Böttger E C

Abstract excerpt

Gene-inactivation techniques were employed to construct a eubacterial organism harbouring a single functional rRNA operon. This mutant of Mycobacterium smegmatis permits replacement of the single remaining rRNA operon with a homologous fragment from a vector-borne gene. By homologous recombinatio...

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Source

Identifiers

PMID: 8971706
DOI: 10.1046/j.1365-2958.1996.01532.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8971706-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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