Article
Molecular analysis of kanamycin and viomycin resistance in Mycobacterium smegmatis by use of the conjugation system.
Journal of bacteriology - 1 Aug 1997
Taniguchi H, Chang B, Abe C, Nikaido Y, Mizuguchi Y, Yoshida S I
Abstract excerpt
We examined the molecular mechanisms of resistance to kanamycin and viomycin in Mycobacterium smegmatis. All of the M. smegmatis strains with high-level kanamycin resistance had a nucleotide substitution from A to G at position 1389 of the 16S rRNA gene (rrs). This position is equivalent to posit...
Topics
- Base Sequence
- Capreomycin
- Conjugation, Genetic
- DNA, Bacterial
- Drug Resistance, Microbial
- Drug Resistance, Multiple
- Genes, Dominant
- Genes, Recessive
- Genome, Bacterial
- Kanamycin Resistance
- Molecular Sequence Data
- Mutation
- Mycobacterium
- Mycobacterium tuberculosis
- RNA, Bacterial
- RNA, Ribosomal, 16S
- Sequence Analysis, RNA
- Viomycin