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Article

Molecular analysis of kanamycin and viomycin resistance in Mycobacterium smegmatis by use of the conjugation system.

Journal of bacteriology - 1 Aug 1997

Taniguchi H, Chang B, Abe C, Nikaido Y, Mizuguchi Y, Yoshida S I

Abstract excerpt

We examined the molecular mechanisms of resistance to kanamycin and viomycin in Mycobacterium smegmatis. All of the M. smegmatis strains with high-level kanamycin resistance had a nucleotide substitution from A to G at position 1389 of the 16S rRNA gene (rrs). This position is equivalent to position 1408 of Escherichia coli, and mutation at this position is known to cause aminoglycoside resistance. Mutations from...

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Identifiers

PMID: 9244267
DOI: 10.1128/jb.179.15.4795-4801.1997
PMCID: PMC179326

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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