Article

PrediXcan: Trait Mapping Using Human Transcriptome Regulation

2015-06-17

Abstract excerpt

<h4>ABSTRACT</h4> Genome-wide association studies (GWAS) have identified thousands of variants robustly associated with complex traits. However, the biological mechanisms underlying these associations are, in general, not well understood. We propose a gene-based association method called PrediXcan that directly tests the molecular mechanisms through which genetic variation affects phenotype. The approach estimate...

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Literature Corpus work: fff2a04f-5467-5fdd-a245-479f5a9ff2a9
DOI: 10.1101/020164

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