Article

Use of murine embryonic fibroblasts to define Toll-like receptor activation and specificity

2004-12-01

Abstract excerpt

Toll-like receptors (TLRs) are critically involved in the innate immune response to bacterial, viral and fungal pathogens. We have studied human peripheral blood mononuclear cells, murine embryonic fibroblasts (MEFs) and a panel of human cell lines, including HEK, HeLa, AGS, ECV304 and U373 cells, for expression of TLR-specific mRNAs and for TLR-ligand dependent cytokine secretion. Peripheral blood cells expressed...

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Literature Corpus work: ffc1e779-0ede-5fd1-94ca-c34e41578322
DOI: 10.1177/09680519040100060701

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