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Article

Toll-like receptor signaling in hematopoietic homeostasis and the pathogenesis of hematologic diseases.

Frontiers of medicine - 1 Sept 2015

Cannova Joseph, Breslin S J Peter, Zhang Jiwang

Abstract excerpt

Toll-like receptors (TLRs), which are found in innate immune cells, are essential mediators of rapid inflammatory responses and appropriate T-cell activation in response to infection and tissue damage. Accumulating evidence suggests that TLR signaling is involved in normal hematopoiesis and specific hematologic pathologies. Particular TLRs and their downstream signaling mediators are expressed not only in...

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Identifiers

PMID: 26297301
DOI: 10.1007/s11684-015-0412-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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