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Article

How important are Toll-like receptors for antimicrobial responses?

23 May 2007

Abstract excerpt

The innate immune system is the primary line of defence against invading pathogenic microbes. Toll-like receptors (TLRs) are a family of membrane receptors which play a pivotal role in sensing a wide range of invading pathogens including bacteria, fungi and viruses. TLR-deficient mice have provided us with immense knowledge on the functioning of individual TLRs. Dysregulation of TLR signalling is linked with a...

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Identifiers

PMID: 17521328
DOI: 10.1111/j.1462-5822.2007.00965.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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