Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Use of murine embryonic fibroblasts to define Toll-like receptor activation and specificity

22 Nov 2004

Abstract excerpt

Toll-like receptors (TLRs) are critically involved in the innate immune response to bacterial, viral and fungal pathogens. We have studied human peripheral blood mononuclear cells, murine embryonic fibroblasts (MEFs) and a panel of human cell lines, including HEK, HeLa, AGS, ECV304 and U373 cells, for expression of TLR-specific mRNAs and for TLR-ligand dependent cytokine secretion. Peripheral blood cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Response and Inflammation
Share to Neonatal Respiratory Health Research
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15588425
DOI: 10.1179/096805104225006516

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Use of murine embryonic fibroblasts to define Toll-like receptor activation and specificityPMID 15588425Read ↗

Use of murine embryonic fibroblasts to define Toll-like receptor activation and specificitySemantic proximity Read ↗

Differential expression of Toll-like receptor 2 in human cellsSemantic proximity Read ↗

Toll-like receptors: a growing family of immune receptors that are differentially expressed and regulated by different leukocytesSemantic proximity Read ↗

Tissue Expression of Human Toll-Like Receptors and Differential Regulation of Toll-Like Receptor mRNAs in Leukocytes in Response to Microbes, Their Products, and CytokinesSemantic proximity Read ↗

Toll-like receptor signaling in hematopoietic homeostasis and the pathogenesis of hematologic diseases.Semantic proximity Read ↗

Toll-like receptor signal transductionSemantic proximity Read ↗

Toll-Like Receptors as Interferon-Regulated Genes and Their Role in DiseaseSemantic proximity Read ↗

How important are Toll-like receptors for antimicrobial responses?Semantic proximity Read ↗

Non-canonical Activation of Human Group 2 Innate Lymphoid Cells by TLR4 SignalingSemantic proximity Read ↗

TLR7 and TLR8 activate distinct pathways in monocytes during RNA virus infectionSemantic proximity Read ↗

ORIGINAL ARTICLE: Quantification and Comparison of Toll‐Like Receptor Expression and Responsiveness in Primary and Immortalized Human Female Lower Genital Tract EpitheliaSemantic proximity Read ↗

Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein useSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.