ORIGINAL ARTICLE: Quantification and Comparison of Toll‐Like Receptor Expression and Responsiveness in Primary and Immortalized Human Female Lower Genital Tract Epithelia

Abstract excerpt

PROBLEM: To better understand innate immune responses to sexually-transmitted infection (STI) and the appropriateness of epithelial cell (EC) models of the vaginal and cervical mucosa, quantified toll-like receptor (TLR) expression from a population of women is needed. METHOD OF STUDY: TLR gene expression was quantified in primary and immortalized endocervical, ectocervical, and vaginal EC from multiple donors....

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