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Article

Differential expression of Toll-like receptor 2 in human cells

1 Mar 2001

Abstract excerpt

Human Toll-like receptor 2 (TLR2) is a receptor for a variety of microbial products and mediates activation signals in cells of the innate immune system. We have investigated expression and regulation of the TLR2 protein in human blood cells and tissues by using two anti-TLR2 mAbs. Only myelomonocytic cell lines expressed surface TLR2. In tonsils, lymph nodes, and appendices, activated B-cells in germinal centers...

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PMID: 11261796
DOI: 10.1189/jlb.69.3.474

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