Article

Non-canonical Activation of Human Group 2 Innate Lymphoid Cells by TLR4 Signaling

2020-10-29

Abstract excerpt

Group 2 innate lymphoid cells (ILC2) are emerging as a critical player in type 2 immunity at barrier sites in response to microbial infections and allergen exposures. Although their classical activators are known to be host epithelial-derived alarmin cytokines IL-33, IL-25 or TSLP, it remains elusive whether ILC2 cells can be activated by directly sensing microbial ligands via pattern-recognition receptors such as...

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Literature Corpus work: 54f5b000-6a3c-5c5e-9b42-3cfe61efa281
DOI: 10.1101/2020.10.29.361345

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