Article

Dendritic cell-specific SMAD3, downstream of JAK2, contributes to inflammation and salt-sensitivity of blood pressure

2023-05-19

Abstract excerpt

<title>Abstract</title> <p>Salt-sensitivity of blood pressure (SSBP), characterized by acute changes in blood pressure with changes in dietary sodium intake, is an independent risk factor for cardiovascular disease and mortality in people with and without hypertension. We previously found that elevated sodium concentration activates antigen presenting cells (APCs), resulting in high blood pressure, but the mechan...

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Literature Corpus work: ffa57372-3ef2-5ca0-86b8-dd387f12a6cc
DOI: 10.21203/rs.3.rs-2908485/v1

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