Article

A sodium-HIF1α axis coordinates immune metabolic reprogramming and mitochondrial remodeling in salt-sensitive hypertension

2026-04-24

Abstract excerpt

<title>Abstract</title> <p>Salt-sensitivity of blood pressure (SSBP) is associated with immune-metabolic dysfunction, yet the mechanism that coordinates sodium exposure, mitochondrial remodeling, and blood pressure response remains undefined. Phenome-wide and laboratory-value association studies (PheWAS and LabWAS) in the All of Us Research Program identified fluid, electrolyte, and acid-base balance disorders an...

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Literature Corpus work: 3830ffdf-15d8-5eba-892f-b28cfa25c47f
DOI: 10.21203/rs.3.rs-9504540/v1

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