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Article

Epigenetic Regulation of Innate and Adaptive Immune Cells in Salt-Sensitive Hypertension

16 Jan 2025

Abstract excerpt

Access to excess dietary sodium has heightened the risk of cardiovascular diseases, particularly affecting individuals with salt sensitivity of blood pressure. Our research indicates that innate antigen-presenting immune cells contribute to rapid blood pressure increases in response to excess sodium intake. Emerging evidence suggests that epigenetic reprogramming, with subsequent transcriptional and metabolic...

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Identifiers

PMID: 39819017
DOI: 10.1161/circresaha.124.325439

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