Article

Human embryo retroviral LTR elements: a pan-primate epigenetic architect contributing to evolution, development, physiological traits, and pathological phenotypes of Modern Humans.

2023-11-26

Abstract excerpt

Evolution created two distinct families of pan-primate endogenous retroviruses, namely HERVL and HERVH, which infected primates’ germline, colonized host genomes, and evolved into the global retroviral genomic regulatory dominion (GRD) operating during human embryogenesis. Retroviral GRD constitutes 8839 highly conserved fixed LTR elements linked to 5444 down-stream target genes forged by evolution into a function...

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Literature Corpus work: 6a3954bf-9bfb-5ab3-bbd5-d2a9d7071d82
DOI: 10.21203/rs.3.rs-3645831/v1

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