Article
Analysis of 8839 pan-primate retroviral LTR elements with regulatory functions during human embryogenesis reveals their global impacts on evolution of Modern Humans
2023-08-07
Abstract excerpt
During millions years of primate evolution, two distinct families of pan-primate endogenous retroviruses, namely HERVL and HERVH, infected primates’ germline, colonized host genomes and evolved to contribute to creation of the global retroviral genomic regulatory dominion (GRD) operating during human embryogenesis. Retroviral GRD constitutes of 8839 highly conserved LTR elements linked to 5444 down-stream target g...
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Identifiers and source
- Literature Corpus work
- b2ef5a43-e1c6-5720-ae4d-9af90e27272a
- DOI
- 10.1101/2023.08.06.552206
