Back to search

Article

Gene ontology-guided analyses of pan-primate regulatory LTR elements contributing to embryogenesis, development of physiological traits and pathological phenotypes of Modern Humans

2024-03-12

Abstract excerpt

Two distinct families of pan-primate endogenous retroviruses, namely HERVL and HERVH, infected primates germline, colonized host genomes, and evolved into the global genomic regulatory dominion (GRD) operating during human embryogenesis (HE). Analyzed in this contribution GRD derived from HERV sequences constitutes 8839 highly conserved fixed LTR elements linked to 5444 down-stream target genes forged by evolution...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
5d6b012d-4942-5362-a071-331dbe53814d
DOI
10.21203/rs.3.rs-4020067/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Gene ontology-guided analyses of pan-primate regulatory LTR elements contributing to embryogenesis, development of physiological traits and pathological phenotypes of Modern HumansDOI 10.21203/rs.3.rs-4020067/v1
Gene ontology-guided proximity placement analyses of pan-primate regulatory LTR elements that contribute to embryogenesis.Semantic proximity
Analysis of 8839 pan-primate retroviral LTR elements with regulatory functions during human embryogenesis reveals their global impacts on evolution of Modern HumansSemantic proximity
Human embryo retroviral LTR elements: a pan-primate epigenetic architect contributing to evolution, development, physiological traits, and pathological phenotypes of Modern Humans.Semantic proximity
Molecular diversity and phenotypic pleiotropy of ancient genomic regulatory loci derived from human endogenous retrovirus type H (HERVH) promoter LTR7 and HERVK promoter LTR5_Hs and their contemporary impacts on pathophysiology of Modern Humans.Semantic proximity
Molecular diversity and phenotypic pleiotropy of genomic regulatory loci derived from human endogenous retrovirus type H (HERVH) promoter LTR7 and HERVK promoter LTR5_Hs and their impacts on pathophysiology of Modern HumansSemantic proximity
Regulatory Features and Functional Specialization of Human Endogenous Retroviral LTRs: A Genome-Wide Annotation and Analysis via HERVariumSemantic proximity
HERVs as building blocks of RNA regulatory architecture in the human genomeSemantic proximity
Analysis of genomic loci harboring 59,732 human-specific regulatory sequences reveals unique to human regulatory patterns associated with brain developmentSemantic proximity
Identification and catalogue of viral transcriptional regulators in human diseasesSemantic proximity
A Catalogue of 59,732 Human-Specific Regulatory Sequences Reveals Unique-to-Human Regulatory Patterns Associated with Virus-Interacting Proteins, Pluripotency, and Brain Development.Semantic proximity
Identification and characterization of the HERV-K (HML-8) group of human endogenous retroviruses in the genomeSemantic proximity
Human Endogenous Retrovirus-K (HML-2)-Related Genetic Variation: Human Genome Diversity and Disease.Semantic proximity
Select a neighboring publication to make it the new centre.