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Systematic investigation reveals extensive Epstein-Barr virus transcriptional regulation of the human genome

2025-07-20

Abstract excerpt

<h4>Summary</h4> We systematically investigate interactions between Epstein-Barr virus (EBV) transcriptional regulators (vTRs) and the human genome. Starting with 16 known and candidate vTRs, we identify nine whose introduction into human cells results in substantial alterations to host gene expression. Genome-scale determination of vTR genomic binding events and alterations to chromatin accessibility reveals a d...

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Identifiers and source

Literature Corpus work
48622070-4b71-5f98-a6f6-29f989f5878e
DOI
10.1101/2025.07.18.665561
Open publication

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Systematic investigation reveals extensive Epstein-Barr virus transcriptional regulation of the human genomeDOI 10.1101/2025.07.18.665561
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