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Gene activation precedes DNA demethylation in response to infection in human dendritic cells

2018-06-29

Abstract excerpt

<h4>ABSTRACT</h4> DNA methylation is considered to be a relatively stable epigenetic mark. Yet, a growing body of evidence indicates that DNA methylation levels can change rapidly, for example, in innate immune cells facing an infectious agent. Nevertheless, the causal relationship between changes in DNA methylation and gene expression during infection remains to be elucidated. Here, we generated time-course data...

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Literature Corpus work
ff72e9c2-ab9d-5ce1-b672-ca303a66de4f
DOI
10.1101/358531
Open publication

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Gene activation precedes DNA demethylation in response to infection in human dendritic cellsDOI 10.1101/358531
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