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Genome-wide promoter analysis of histone modifications in human monocyte-derived antigen presenting cells

18 Nov 2010

Abstract excerpt

BACKGROUND: Monocyte-derived macrophages and dendritic cells (DCs) are important in inflammatory processes and are often used for immunotherapeutic approaches. Blood monocytes can be differentiated into macrophages and DCs, which is accompanied with transcriptional changes in many genes, including chemokines and cell surface markers. RESULTS: To study the chromatin modifications associated with this...

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PMID: 21087476
DOI: 10.1186/1471-2164-11-642

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