Article

Epigenetic landscape of the H3K27me3 mark in macrophages transformed by <i>Theileria annulata</i>

2025-01-06

Abstract excerpt

Theileria annulata and T. parva are obligate intracellular parasites that induce bovine leukocyte transformation leading to uncontrolled proliferation and heightened dissemination of infected leukocytes. Early passage T. annulata -transformed macrophages are virulent, but with long-term culture, they become attenuated for dissemination. Loss of dissemination is restored when TGF-β2-mediated signaling is re-estab...

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Literature Corpus work: d03e23f3-7656-5ec2-839f-43d0bab19182
DOI: 10.1101/2025.01.06.631474

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