Article

Exploring repositioning opportunities and side-effects of statins: a Mendelian randomization study of HMG-CoA reductase inhibition with 55 complex traits

2017-07-30

Abstract excerpt

Statin is one of the most commonly prescribed medications worldwide. Besides reduction of cardiovascular risks, statins have been proposed for the prevention or treatment of other disorders, but results from clinical studies are mixed. There are also controversies concerning the adverse effects caused by statins. In this study we employed a Mendelian randomization (MR) approach across a wide range of complex trait...

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Literature Corpus work: ff5ba49e-0108-5e23-8b4f-fb91651af404
DOI: 10.1101/170241

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