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Mendelian Randomization Reveals the Role of HMGCR in Pulmonary Arterial Hypertension Treatment, Independent of LDL Cholesterol Concentration

2023-10-03

Abstract excerpt

<h4>Introduction</h4> Specific lipid-reducing therapeutics, including statins, are known for mitigating cardiovascular diseases due to their comprehensive benefits including anti-inflammatory properties, antioxidative stress response, and enhancement of endothelial function. The objective of our study was to determine the causative impact of lipid-reducing agents (HMGCR inhibitors, PCSK9 inhibitors, and NPC1L1 inh...

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Literature Corpus work
5e7ec7d4-e7ae-5bc8-8a78-45ed714c0b13
DOI
10.1101/2023.10.02.23295606
Open publication

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Mendelian Randomization Reveals the Role of HMGCR in Pulmonary Arterial Hypertension Treatment, Independent of LDL Cholesterol ConcentrationDOI 10.1101/2023.10.02.23295606
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