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Knockdown of PR-DUB subunit <i>calypso</i> in the developing <i>Drosophila</i> eye and wing results in mis-patterned tissues with altered size and shape

2025-01-09

Abstract excerpt

<h4>ABSTRACT</h4> The deubiquitinating enzyme BAP1, the catalytic subunit of the PR-DUB complex, is implicated in several cancers, in the familial cancer syndrome BAP1 Tumor Predisposition Syndrome, and in the neurodevelopmental disorder Küry -Isidor syndrome. In Drosophila, there are numerous reports in the literature describing developmental patterning phenotypes for several chromatin regulators including the...

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Literature Corpus work
ff49139f-0404-5c95-b0f0-508189e29165
DOI
10.1101/2025.01.09.631961
Open publication

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Knockdown of PR-DUB subunit <i>calypso</i> in the developing <i>Drosophila</i> eye and wing results in mis-patterned tissues with altered size and shapeDOI 10.1101/2025.01.09.631961
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