Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polycomb silencing of the Drosophila 4E-BP gene regulates imaginal disc cell growth.

Developmental biology - 1 Aug 2013

Mason-Suares Heather, Tie Feng, Yan Christopher M, Harte Peter J

Abstract excerpt

Polycomb group (PcG) proteins are best known for their role in maintaining stable, mitotically heritable silencing of the homeotic (HOX) genes during development. In addition to loss of homeotic gene silencing, some PcG mutants also have small imaginal discs. These include mutations in E(z), Su(z)12, esc and escl, which encode Polycomb repressive complex 2 (PRC2) subunits. The cause of this phenotype is not...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Crosses, Genetic
Share to Drosophila melanogaster
Share to Drosophila Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Silencing

Share to Intracellular Signaling Peptides and Proteins

Share to Peptide Initiation Factors

Share to Polycomb Repressive Complex 1

Share to Sequence Homology, Nucleic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 23523430
DOI: 10.1016/j.ydbio.2013.03.011
PMCID: PMC4416090

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polycomb silencing of the Drosophila 4E-BP gene regulates imaginal disc cell growth.PMID 23523430Read ↗

Dynamic regulation by polycomb group protein complexes controls pattern formation and the cell cycle in Drosophila.Semantic proximity Read ↗

Knockdown of PR-DUB subunit calypso in the developing Drosophila eye and wing results in mis-patterned tissues with altered size and shape.Semantic proximity Read ↗

Analysis of a polycomb group protein defines regions that link repressive activity on nucleosomal templates to in vivo function.Semantic proximity Read ↗

Knockdown of PR-DUB subunit <i>calypso</i> in the developing <i>Drosophila</i> eye and wing results in mis-patterned tissues with altered size and shapeSemantic proximity Read ↗

Identification of regulators of the three-dimensional polycomb organization by a microscopy-based genome-wide RNAi screen.Semantic proximity Read ↗

The cramped gene of Drosophila is a member of the Polycomb-group, and interacts with mus209, the gene encoding Proliferating Cell Nuclear Antigen.Semantic proximity Read ↗

In vivo regulation of E2F1 by Polycomb group genes in Drosophila.Semantic proximity Read ↗

A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression.Semantic proximity Read ↗

A screen for new trithorax group genes identified little imaginal discs, the Drosophila melanogaster homologue of human retinoblastoma binding protein 2.Semantic proximity Read ↗

A role of polycomb group genes in the regulation of gap gene expression in Drosophila.Semantic proximity Read ↗

The Polycomb group gene Posterior Sex Combs encodes a chromosomal protein.Semantic proximity Read ↗

Transcription-independent function of Polycomb group protein PSC in cell cycle control.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.