Article

Model-based Evaluation of Connexin Hemichannel Permeability

2025-06-24

Abstract excerpt

Connexin (Cx) hemichannels represent a growing facet of Cx research. Hemichannels are hexamers of Cx subunits that are historically thought of as substrates of intercellular gap junction channels formed when two hemichannels from neighboring cells dock. Hemichannels, however, can function in the absence of docking and have been shown to play important roles in transmembrane signaling. There are 21 different Cx iso...

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Literature Corpus work: ff37f1df-23c4-5181-95d0-2ec109494a72
DOI: 10.1101/2025.06.19.660562

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