Article

FETCH: A platform for high-throughput quantification of gap junction hemichannel docking

2021-06-07

Abstract excerpt

<h4>ABSTRACT</h4> Gap junctions are membrane spanning channels that connect the cytoplasm of apposed cells, allowing for the passage of small molecules and ions. They are formed by the connexin (Cx) family of proteins which assemble into hexameric hemichannels on each cell and dock to create gap junctional channels between two cells. Despite importance of various Cx isoforms in human physiology and disease, avail...

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Literature Corpus work: dce352ae-1027-5158-9ddd-e9df5f2b74e5
DOI: 10.1101/2021.06.07.447352

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