Article
A novel voltage clamp/dye uptake assay reveals saturable transport of molecules through CALHM1 and connexin channels
2020-02-15
Abstract excerpt
<h4>ABSTRACT</h4> Channels that are permeable to small molecules such as ATP, in addition to atomic ions, are emerging as important regulators in health and disease. Nonetheless, mechanisms of molecular permeation and selectivity of these channels remain mostly unexplored due to the lack of quantitative methodologies. To address this need, we developed a novel two-electrode voltage clamp (TEVC)/dye uptake assay t...
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Identifiers and source
- Literature Corpus work
- 9e07b79f-9310-550a-bcc8-bed78be56c8a
- DOI
- 10.1101/2020.02.15.950923
