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A novel voltage clamp/dye uptake assay reveals saturable transport of molecules through CALHM1 and connexin channels

2020-02-15

Abstract excerpt

<h4>ABSTRACT</h4> Channels that are permeable to small molecules such as ATP, in addition to atomic ions, are emerging as important regulators in health and disease. Nonetheless, mechanisms of molecular permeation and selectivity of these channels remain mostly unexplored due to the lack of quantitative methodologies. To address this need, we developed a novel two-electrode voltage clamp (TEVC)/dye uptake assay t...

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Literature Corpus work
9e07b79f-9310-550a-bcc8-bed78be56c8a
DOI
10.1101/2020.02.15.950923
Open publication

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A novel voltage clamp/dye uptake assay reveals saturable transport of molecules through CALHM1 and connexin channelsDOI 10.1101/2020.02.15.950923
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