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Article

Pathological hemichannels associated with human Cx26 mutations causing Keratitis-Ichthyosis-Deafness syndrome.

Biochimica et biophysica acta - 1 Aug 2012

Levit Noah A, Mese Gulistan, Basaly Mena-George R, White Thomas W

Abstract excerpt

Connexin (Cx) proteins form intercellular gap junction channels by first assembling into single membrane hemichannels that then dock to connect the cytoplasm of two adjacent cells. Gap junctions are highly specialized structures that allow the direct passage of small molecules between cells to maintain tissue homeostasis. Functional activity of nonjunctional hemichannels has now been shown in several experimental...

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Identifiers

PMID: 21933663
DOI: 10.1016/j.bbamem.2011.09.003
PMCID: PMC3245810

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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