Article

Large-pore connexin hemichannels function as molecule transporters independently of ion conduction

2024-02-20

Abstract excerpt

<h4>ABSTRACT</h4> Connexin hemichannels were identified as the first members of the eukaryotic large-pore channel family that mediate permeation of both atomic ions and small molecules between the intracellular and extracellular environments. The conventional view is that their pore is a large passive conduit through which both ions and molecules diffuse in a similar manner. In stark contrast to this notion, we d...

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Literature Corpus work: 256b6bcc-02f0-5ebe-8548-537b19fed8de
DOI: 10.1101/2024.02.20.581300

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