Article
Structural analysis of key gap junction domains--Lessons from genome data and disease-linked mutants.
Seminars in cell & developmental biology - 1 Feb 2016
Bai Donglin
Abstract excerpt
A gap junction (GJ) channel is formed by docking of two GJ hemichannels and each of these hemichannels is a hexamer of connexins. All connexin genes have been identified in human, mouse, and rat genomes and their homologous genes in many other vertebrates are available in public databases. The protein sequences of these connexins align well with high sequence identity in the same connexin across different...
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