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Connexin hemichannels in the lens

1 Jan 2014

Abstract excerpt

The normal function and survival of cells in the avascular lens is facilitated by intercellular communication through an extensive network of gap junctions formed predominantly by three connexins (Cx43, Cx46, and Cx50). In expression systems, these connexins can all induce hemichannel currents, but other lens proteins (e.g., pannexin1) can also induce similar currents. Hemichannel currents have been detected in...

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Identifiers

PMID: 24575044
DOI: 10.3389/fphys.2014.00020

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