Article

Distinct functions of tissue-resident and circulating memory Th2 cells in allergic airway disease

2020-03-27

Abstract excerpt

<h4>ABSTRACT</h4> Memory CD4 + T helper type 2 (Th2) cells are critical in driving allergic asthma pathogenesis, yet the mechanisms whereby tissue-resident memory Th2 cells (Th2 Trm) and circulating memory Th2 cells collaborate in vivo remain unclear. Here, using a house dust mite (HDM) model of allergic asthma and parabiosis, we demonstrate that Th2 Trm and circulating memory Th2 cells perform non-redundant fu...

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Identifiers and source

Literature Corpus work: ff05e869-40ff-5610-a091-43eefe0cc239
DOI: 10.1101/2020.03.25.006858

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