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Functional heterogeneity of human skin-resident memory T cells in health and disease.

Immunological reviews - 1 Jul 2023

Strobl Johanna, Haniffa Muzlifah

Abstract excerpt

The human skin is populated by a diverse pool of memory T cells, which can act rapidly in response to pathogens and cancer antigens. Tissue-resident memory T cells (TRM ) have been implicated in range of allergic, autoimmune and inflammatory skin diseases. Clonal expansion of cells with TRM properties is also known to contribute to cutaneous T-cell lymphoma. Here, we review the heterogeneous phenotypes,...

Topics

Humans
Memory T Cells
Immunologic Memory
Skin
Neoplasms
Phenotype
CD8-Positive T-Lymphocytes

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37144705
DOI: 10.1111/imr.13213
PMCID: PMC10952320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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