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Progenitor T cells drive chronic pulmonary type 2 inflammation

2025-10-05

Abstract excerpt

Type 2 inflammation unfolds over time and is coordinated by remarkably durable CD4+ Th2 cell responses, standing in contrast to the collapse of adaptive immunity seen in chronic infection and malignancy. In experimental models, short-lived Th2 effector cells and type 2 innate lymphocytes (ILC2) contribute to acute type 2 inflammation, yet the cellular architecture that drives chronic type 2 inflammation and preven...

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Identifiers and source

Literature Corpus work
60250f65-f864-5cb2-8165-cd4c95841c04
DOI
10.1101/2025.10.03.680133
Open publication

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Progenitor T cells drive chronic pulmonary type 2 inflammationDOI 10.1101/2025.10.03.680133
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