Article

Mast cell populations shift and adapt transcription profiles during the resolution of allergic airway inflammation

2025-03-13

Abstract excerpt

<title>Abstract</title> <p>Asthma is a chronic lung disease characterized by recurrent acute inflammation and periods of resolution. To determine whether inflammation-induced lung mast cell (MC) populations persist or undergo phenotypic shifts during the resolution phase, we performed cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq) of enriched lineage- CD45+ ST2+ FcεRI+ lung cells and im...

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Literature Corpus work: a77e8d12-9b39-5053-abd2-6ecbaf7e4ec4
DOI: 10.21203/rs.3.rs-6115255/v1

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