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Network-based analysis of genome-wide biobank data boosts discovery of genetic associations in psoriasis

2025-12-07

Abstract excerpt

Psoriasis is a common autoimmune disease with a strong genetic component. Targeting the IL-23/IL-17 pathways for the treatment of moderate-severe psoriasis has proven successful, which makes it a good benchmark for other drug discovery approaches. Genome Wide Association Studies (GWAS) identify genetic loci associated with a phenotype (e.g. disease). However, using identified loci to understand the disease mechan...

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Literature Corpus work
ff02942d-7a7b-50a0-8468-ca1fc4dcd146
DOI
10.64898/2025.12.05.25340137
Open publication

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Network-based analysis of genome-wide biobank data boosts discovery of genetic associations in psoriasisDOI 10.64898/2025.12.05.25340137
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