Article

Network-based analysis of genome-wide biobank data boosts discovery of genetic associations in psoriasis

2026-03-16

Abstract excerpt

<title>Abstract</title> <p>Psoriasis is a common autoimmune disease with a strong genetic component. Targeting the \textit{IL-23/IL-17} pathways for the treatment of moderate-severe psoriasis has proven successful, which makes it a good benchmark for other drug discovery approaches. Genome Wide Association Studies (GWAS) identify genetic loci associated with a phenotype (e.g. disease). However, using identified l...

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Literature Corpus work: 1b3ee8b1-af48-57eb-8b38-47c96ab79449
DOI: 10.21203/rs.3.rs-8700526/v1

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