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Article

A Transcriptome-Wide Analysis of Psoriasis: Identifying the Potential Causal Genes and Drug Candidates.

International journal of molecular sciences - 20 Jul 2023

Jeong Yeonbin, Song Jaeseung, Lee Yubin, Choi Eunyoung, Won Youngtae, Kim Byunghyuk, Jang Wonhee

Abstract excerpt

Psoriasis is a chronic inflammatory skin disease characterized by cutaneous eruptions and pruritus. Because the genetic backgrounds of psoriasis are only partially revealed, an integrative and rigorous study is necessary. We conducted a transcriptome-wide association study (TWAS) with the new Genotype-Tissue Expression version 8 reference panels, including some tissue and multi-tissue panels that were not used...

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Share to Gene Expression Profiling
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 37511476
DOI: 10.3390/ijms241411717
PMCID: PMC10380797

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