Article

Harnessing GPT-4 for Automated Curation of E3-Substrate Relationships in the Ubiquitin-Proteasome System

2024-10-21

Abstract excerpt

The ubiquitin-proteasome system (UPS) is a complex regulatory network involving around 600 E3 ligases that collectively govern the stability of the human proteome by targeting thousands of proteins for degradation. Understanding this network requires integrating vast amounts of information on gene and protein interactions scattered across unstructured literature. Historically, manual curation has been the gold sta...

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Literature Corpus work: feec540b-5db3-55f4-a552-3cb43ac71285
DOI: 10.1101/2024.10.20.619305

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