Article

Cancer histone H2A.Z missense mutations disrupt function through distinct local and allosteric effects

2026-01-12

Abstract excerpt

<title>Abstract</title> <p> H2A.Z is a conserved variant of histone H2A that functions in a wide range of processes including transcriptional, chromatin organization, and genome stability, but whose exact role in the cell remains incompletely understood. A growing body of literature highlights the utility of cancer histone missense mutations in revealing fundamental aspects of histone structure and function not...

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Literature Corpus work: fea9aff7-e7cd-5d77-aefb-1f0a690c9bae
DOI: 10.21203/rs.3.rs-8484515/v1

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