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Article

Nucleosome alterations caused by mutations at modifiable histone residues in Saccharomyces cerevisiae.

Scientific reports - 26 Oct 2015

Liu Hongde, Wang Pingyan, Liu Lingjie, Min Zhu, Luo Kun, Wan Yakun

Abstract excerpt

Nucleosome organization exhibits dynamic properties depending on the cell state and environment. Histone proteins, fundamental components of nucleosomes, are subject to chemical modifications on particular residues. We examined the effect of substituting modifiable residues of four core histones with the non-modifiable residue alanine on nucleosome dynamics. We mapped the genome-wide nucleosomes in 22 histone...

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Identifiers

PMID: 26498326
DOI: 10.1038/srep15583
PMCID: PMC4620441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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