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Article

Global analysis for functional residues of histone variant Htz1 using the comprehensive point mutant library.

Genes to cells : devoted to molecular & cellular mechanisms - 1 May 2011

Kawano Ayumi, Hayashi Yohei, Noguchi Shuhei, Handa Hiroshi, Horikoshi Masami, Yamaguchi Yuki

Abstract excerpt

Histone variants perform unique functions and are deposited onto DNA by mechanisms distinct from those of canonical histones. The H2A variant, H2A.Z, also known as Htz1 in Saccharomyces cerevisiae, is not uniformly distributed across the genome but facilitates transcriptional activation at target gene promoters and anti-silencing at heterochromatin loci. Htz1 is also involved in DNA replication, DNA repair,...

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PMID: 21470346
DOI: 10.1111/j.1365-2443.2011.01512.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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