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Article

Regulation of Human Erythroferrone Expression

2026-07-03

Abstract excerpt

Erythroferrone (ERFE) is an erythroblast-secreted hormone that suppresses hepatic hepcidin expression to increase iron availability for erythropoiesis, ensuring recovery from anaemia. ERFE excess drives iron overload in disorders of ineffective erythropoiesis. Despite its pivotal role in systemic iron homeostasis and diseases of erythropoiesis, ERFE’s molecular regulation has remained undefined. Here, we applied a...

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Literature Corpus work
fea17b37-272b-57e8-b912-1d15730b282e
DOI
10.64898/2026.07.02.735786
Open publication

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Regulation of Human Erythroferrone ExpressionDOI 10.64898/2026.07.02.735786
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