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Advances in understanding the mechanisms of erythropoiesis in homeostasis and disease

21 Jul 2016

Abstract excerpt

Anaemia or decreased blood haemoglobin is the most common blood disorder often characterized by reduced red blood cell (RBC) numbers. RBCs are produced from differentiation and commitment of haematopoietic stem cells to the erythroid lineage by a process called erythropoiesis. Coordination of erythropoietin receptor signalling with several erythroid transcription factors including GATA1 is essential for this...

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PMID: 27442953
DOI: 10.1111/bjh.14194

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