Article

Landscape of Cell Heterogeneity and Evolutionary Trajectory in Ulcerative Colitis-associated Colon Cancer Revealed by Single-cell Rna Sequencing

2020-08-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Patients with colitis-associated cancer (CAC), a particular kind of colorectal cancer that develops from inflammatory bowel diseases (IBDs), have an earlier morbidity and a poorer prognosis. However, in CAC, single cell transcriptome analysis of the microenvironment composition and characteristics has yet to be performed. To understand the intra-tumor heterogene...

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Literature Corpus work: fe9fd7b6-1632-568a-aa4d-5c9580cfda5d
DOI: 10.21203/rs.3.rs-60886/v1

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