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Understanding the cellular and molecular heterogeneity in colorectal cancer through the use of single-cell RNA sequencing

2 Apr 2025

Abstract excerpt

The very prevalent nature, genetic variability, and intricate tumor microenvironment (TUME) of colorectal cancer (COREC) are its defining features. In order to better understand the molecular and cellular make-up of COREC, this work used single-cell RNA sequencing (SRNAS) to isolate and characterize important cell types as well as their interactions within the TUME. Our analysis of 51,204 cells yielded six...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40163910
DOI: 10.1016/j.tranon.2025.102374

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