Back to search

Article

Identification of a novel T cell-related signature to predict prognosis in colorectal cancer via integrating single-cell and bulk RNA sequencing

2024-02-01

Abstract excerpt

<h4>Background: </h4> T cells, the key mediators of tumor destruction, have a considerable impact on tumor prognosis. However, the clinical significance of T cell-associated biomarkers in colorectal cancer (CRC) haven’t been well understood. The aim of this study was to investigate the expression profile of T cell marker genes in CRC and develop a prognostic signature based on these genes. <h4>Methods: </h4>: Sin...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b84a5aed-5291-5027-9ac9-c12379eba528
DOI
10.21203/rs.3.rs-3909225/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Identification of a novel T cell-related signature to predict prognosis in colorectal cancer via integrating single-cell and bulk RNA sequencingDOI 10.21203/rs.3.rs-3909225/v1
Integrated single-cell and bulk RNA-seq for constructing a prognostic risk model of immune-related genes in colorectal cancerSemantic proximity
Integrated single-cell and bulk RNA-seq analysis reveals a novel T-cell signature for prognosis and treatment response in colorectal cancerSemantic proximity
Establishing and validating a prognostic model for colorectal cancer patients by integrating data from single-cell RNA sequencing and bulk RNA sequencingSemantic proximity
Landscape of Cell Heterogeneity and Evolutionary Trajectory in Ulcerative Colitis-associated Colon Cancer Revealed by Single-cell Rna SequencingSemantic proximity
Single-Cell Transcriptome Analysis Reveals Heterogeneity and Convergence of the Tumor Microenvironment in CRCSemantic proximity
Single-Cell Transcriptomic Profiling Reveals T-Cell Functional Shifts in Primary Versus Metastatic Colorectal CancerSemantic proximity
Single-cell and spatial transcriptomic analysis reveals tumor cell heterogeneity and underlying molecular program in colorectal cancerSemantic proximity
Single Cell Transcriptome in Colorectal Cancer—Current Updates on Its Application in Metastasis, Chemoresistance and the Roles of Circulating Tumor CellsSemantic proximity
Intratumoral Heterogeneity of CRC Revealed by Single-Cell Transcriptome Analysis, which Results in Poor Prognosis Clinical OutcomesSemantic proximity
Integrated Single‐Cell RNA ‐Seq Reveals Immunosuppressive Mechanisms of Treg Cell Differentiation and Tumor Microenvironment Interactions in Colorectal CancerSemantic proximity
Single-cell technology reveals the crosstalk between tumor cells and immune cells: driving immune signal transduction and inflammation-mediated cardiac dysfunction in the tumor microenvironment of colorectal cancerSemantic proximity
Single-cell transcriptional profiling reveals the heterogenicity in colorectal cancerSemantic proximity
Select a neighboring publication to make it the new centre.