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Article

Single-cell transcriptional profiling reveals the heterogenicity in colorectal cancer

1 Aug 2019

Abstract excerpt

BACKGROUND: Colorectal Cancer (CRC) is a highly heterogeneous disease. RNA profiles of bulk tumors have enabled transcriptional classification of CRC. However, such ways of sequencing can only target a cell colony and obscure the signatures of distinct cell populations. Alternatively, single-cell RNA sequencing (scRNA-seq), which can provide unbiased analysis of all cell types, opens the possibility to map...

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PMID: 31441872
DOI: 10.1097/md.0000000000016916

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