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Article

Restriction Enzyme Based Enriched L1Hs sequencing (REBELseq)

2019-07-20

Abstract excerpt

Long interspersed element-1 retrotransposons (LINE-1 or L1) are ~6 kb mobile DNA elements implicated in the origins of many Mendelian and complex diseases. The actively retrotransposing L1s are mostly limited to the L1 human specific Ta subfamily. In this manuscript, we present REBELseq as a method for the construction of differentially amplified next-generation sequencing libraries and bioinformatic identificatio...

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Literature Corpus work
fe9b665b-d120-5586-a5d6-fc543f963a03
DOI
10.1101/710095
Open publication

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Restriction Enzyme Based Enriched L1Hs sequencing (REBELseq)DOI 10.1101/710095
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